{"id":20,"date":"2026-09-22T19:35:58","date_gmt":"2026-09-22T19:35:58","guid":{"rendered":"https:\/\/zdravljeihrana.com\/?p=20"},"modified":"2026-09-23T10:16:23","modified_gmt":"2026-09-23T10:16:23","slug":"stanja-u-kojima-vitamin-c-odmaze-vise-nego-sto-pomaze","status":"publish","type":"post","link":"https:\/\/zdravljeihrana.com\/?p=20","title":{"rendered":"Stanja u kojima vitamin C odma\u017ee vi\u0161e nego \u0161to poma\u017ee"},"content":{"rendered":"\n<p class=\"wp-block-paragraph\"><strong>Vitamin C u\u017eiva gotovo besprijekoran ugled. Djeluje kao antioksidans, poma\u017ee imunitetu, ubrzava zacjeljivanje rana i ve\u0107ina ljudi ga smatra dodatkom s kojim &#8220;ne mo\u017eete pretjerati&#8221;. No za odre\u0111ene skupine ljudi i kod odre\u0111enih zdravstvenih stanja, visoke doze vitamina C nisu bezazlene. U nekim slu\u010dajevima mogu izazvati ozbiljne komplikacije \u2013 od bubre\u017enih kamenaca do te\u0161ke anemije.<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Mu\u0161karci i bubre\u017eni kamenci<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Ovo je najbolje dokumentiran problem. <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/23381591\/\">Veliko istra\u017eivanje u \u0160vedskoj<\/a> pratilo je preko 22 tisu\u0107e mu\u0161karaca srednje i starije dobi tijekom 11 godina. Mu\u0161karci koji su redovito uzimali dodatke vitamina C imali su gotovo dvostruko ve\u0107u u\u010destalost bubre\u017enih kamenaca u odnosu na one koji nisu uzimali nikakve dodatke prehrani.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Sli\u010dno su pokazala i <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/26463139\/\">dva velika ameri\u010dka istra\u017eivanja koja su pratila zdravstvene djelatnike i medicinske sestre<\/a> kroz vi\u0161e od deset godina. Kod mu\u0161karaca koji su uzimali 1000 mg vitamina C dnevno ili vi\u0161e, rizik od bubre\u017enih kamenaca bio je zna\u010dajno pove\u0107an. Kod \u017eena taj obrazac nije zabilje\u017een, a dodatno je zanimljivo da vitamin C unesen putem hrane (vo\u0107e, povr\u0107e) nije bio povezan s pove\u0107anim rizikom \u2013 problem se javljao isklju\u010divo kod visokih doza iz dodataka prehrani.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Razlog je biolo\u0161ki jasan: dio vitamina C u tijelu se pretvara u oksalat, tvar koja se izlu\u010duje mokra\u0107om i koja je jedan od glavnih sastojaka naj\u010de\u0161\u0107eg tipa bubre\u017enih kamenaca. <a href=\"https:\/\/www.renalandurologynews.com\/news\/urology\/kidney-stones\/kidney-stone-risk-in-men-linked-to-vitamin-c-intake\/\">Kod doza od 2 grama dnevno, izlu\u010divanje oksalata u mokra\u0107i poraslo je za oko 22 posto<\/a>.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Preoptere\u0107enje \u017eeljezom (hemokromatoza)<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Vitamin C poja\u010dava upijanje \u017eeljeza iz hrane u crijevima \u2013 zato ga se \u010desto preporu\u010duje uz biljne izvore \u017eeljeza kod anemije. No ta ista osobina postaje problem kod ljudi koji ve\u0107 imaju previ\u0161e \u017eeljeza u tijelu, poput osoba s nasljednom hemokromatozom (genetskim poreme\u0107ajem koji uzrokuje pretjerano nakupljanje \u017eeljeza u jetri, srcu i drugim organima).<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Kod zdravih ljudi i onih koji nose samo jednu kopiju gena za hemokromatozu, tijelo ima dobre mehanizme koji sprje\u010davaju da vi\u0161ak vitamina C poremeti ravnote\u017eu \u017eeljeza. No <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/10218143\/\">kod osoba koje boluju od pune, te\u017ee forme hemokromatoze, stru\u010dnjaci savjetuju oprez<\/a> jer u\u010dinak visokih doza vitamina C na apsorpciju \u017eeljeza kod te skupine nikad nije sustavno istra\u017een, a postoje\u0107i opisi slu\u010dajeva upu\u0107uju na mogu\u0107 rizik.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Rijedak, ali ozbiljan rizik: manjak enzima G6PD<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">G6PD manjak je nasljedni poreme\u0107aj kod kojeg crvena krvna zrnca nedostaju enzim koji ih \u0161titi od oksidativnog stresa. Osobe s ovim manjkom poznate su po tome \u0161to moraju izbjegavati odre\u0111enu hranu (npr. bob) i lijekove koji mogu izazvati raspad crvenih krvnih zrnaca.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Vitamin C se uglavnom smatra antioksidansom, ali u vrlo visokim dozama, posebno kada se daje izravno u venu, mo\u017ee djelovati suprotno o\u010dekivanom i izazvati upravo takav oksidativni stres. <a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC8857720\/\">Pregled dostupnih opisa slu\u010dajeva prona\u0161ao je 14 zabilje\u017eenih slu\u010dajeva raspada crvenih krvnih zrnaca povezanih s vitaminom C<\/a>, od kojih je ve\u0107ina bila kod mu\u0161karaca s manjkom G6PD enzima. Doze su se kretale od 1 do \u010dak 200 grama dnevno, a ve\u0107ina slu\u010dajeva dogodila se kod primjene izravno u venu.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><a href=\"https:\/\/www.scienceopen.com\/hosted-document?doi=10.24911\/ejmcr\/173-1544044604\">Opisan je i slu\u010daj mu\u0161karca koji je razvio te\u0161ku anemiju i drugu ozbiljnu komplikaciju krvi<\/a> nakon \u0161to je primio 395 grama vitamina C izravno u venu u sklopu alternativne terapije, a naknadno je otkriveno da ima nedijagnosticirani manjak G6PD enzima.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Postoje i noviji, bla\u017ei pogledi na ovaj rizik \u2013 <a href=\"https:\/\/ashpublications.org\/bloodrci\/article\/1\/1\/100006\/536416\/Self-administered-vitamin-C-increased-red-blood\">jedan pregled stru\u010dnjaka kasnije je preispitao tu preporuku<\/a> i ocijenio da standardne doze vitamina C kod G6PD manjka nose vrlo nizak rizik, dok problem ostaje uglavnom vezan uz ekstremno visoke intravenske doze.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Va\u017eno je naglasiti da ni\u017ee, uobi\u010dajene doze vitamina C (do nekoliko stotina miligrama dnevno kroz usta) nisu povezane s ovim rizikom \u2013 problem se javlja kod ekstremno visokih doza, \u010desto onih koje se koriste u alternativnim &#8220;intravenskim vitaminskim terapijama&#8221;.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Kratki pregled \u2013 tko treba biti oprezan<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Mu\u0161karci sa sklono\u0161\u0107u bubre\u017enim kamencima<\/strong> \u2013 izbjegavati visoke doze dodataka (preko 1000 mg dnevno), unos kroz hranu nije problemati\u010dan<\/li>\n\n\n\n<li><strong>Osobe s hemokromatozom ili drugim poreme\u0107ajima vi\u0161ka \u017eeljeza<\/strong> \u2013 izbjegavati dodatke vitamina C bez dogovora s lije\u010dnikom<\/li>\n\n\n\n<li><strong>Osobe s manjkom G6PD enzima<\/strong> \u2013 izbjegavati vrlo visoke doze, posebno intravenske<\/li>\n<\/ul>\n\n\n\n<p class=\"wp-block-paragraph\">Za ve\u0107inu zdravih ljudi, umjerene doze vitamina C iz hrane ili standardnih dodataka prehrani (do 500-1000 mg dnevno) ostaju sigurne. Problemi opisani u ovom tekstu javljaju se uglavnom kod vrlo visokih doza ili kod specifi\u010dnih, ve\u0107 postoje\u0107ih zdravstvenih stanja.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><em>Disclaimer: Ovaj tekst ima informativni karakter i temelji se na dostupnim znanstvenim istra\u017eivanjima. Ne predstavlja medicinski savjet niti zamjenu za konzultaciju s lije\u010dnikom, nefrologom, hematologom, onkologom ili nutricionistom. Ako imate neko od navedenih zdravstvenih stanja ili uzimate visoke doze dodataka prehrani, o tome se posavjetujte sa svojim lije\u010dnikom.<\/em><\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Vitamin C u\u017eiva gotovo besprijekoran ugled. Djeluje kao antioksidans, poma\u017ee imunitetu, ubrzava zacjeljivanje rana i ve\u0107ina ljudi ga<\/p>\n","protected":false},"author":1,"featured_media":91,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[10],"tags":[15,14,16],"class_list":["post-20","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-suplementi","tag-bubrezni-kamenac","tag-vitamin-c","tag-vitaminc-i-zdravlje"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.5 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Stanja u kojima vitamin C odma\u017ee vi\u0161e nego \u0161to poma\u017ee - Zdravlje i hrana<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/zdravljeihrana.com\/?p=20\" \/>\n<meta property=\"og:locale\" content=\"hr_HR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Stanja u kojima vitamin C odma\u017ee vi\u0161e nego \u0161to poma\u017ee - Zdravlje i hrana\" \/>\n<meta property=\"og:description\" content=\"Vitamin C u\u017eiva gotovo besprijekoran ugled. 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